Association between triglyceride and all-cause mortality and cardiovascular outcomes in heart failure patients: a territory-wide study in Hong Kong

Abstract Funding Acknowledgements Type of funding sources: None. Objectives To determine the association between levels triglyceride (TG) and all-cause mortality cardiovascular outcomes. evaluate concentration TG associated with lower range lowest risk adverse outcomes in heart failure (HF) patients. Methods Using a previously validated territory-wide clinical information registry, all eligible patients HF (N=147 396) from 1996 to 2020 were enrolled. Levels time-weighted evaluated on continuous scale using restricted cubic spline curves by categories Cox proportional hazards regression model. The primary death (CVD). Secondary include cause-specific incident events. Results Among 147 396 patients, mean age was 70.0±12.5 years 73 571 (49.9%) male. J-shaped, low high an increased mortality, CVD mortality. Compared individuals 1.14 2.85 mmol/L, multivariable-adjusted hazard ratio (HR) for 1.39 (95% confidence interval [CI] 1.35 1.44) concentrations less than 0.71 mmol/L 1.97 CI, 1.67 2.32) more 5.60 mmol/L. 1.84 Similar results seen males females, or without lipid-lowering treatment, Conclusion In population, found at